We are looking for new group members with passion, talent, and grit! You will have the chance to work on grand challenges in the field of immune regulation and tumour immunity. You will be responsible for driving your research, identifying the most important questions, designing and performing experiments and publishing findings. We are happy to consider and support applications for talented postdoctoral researchers, PhD and Master's students. Please send me an email stating briefly why you are interested in joining the group and attaching a CV.

DPhil (PhD) in Cancer Science

I originally trained in Veterinary Medicine before undertaking a PhD in Immunology at the Roslin Institute in the University of Edinburgh. Following postdoctoral work at the Francis Crick Institute and the University of Cambridge, I joined the Centre for Immuno-Oncology at the University of Oxford as a Group Leader in 2025.

A major contribution of our research was discovery of the mechanisms underlying the anti-metastatic effects of aspirin. Our work demonstrated that inhibitors of cyclooxygenase 1 (COX-1), including aspirin, enhance immunity to cancer metastasis by releasing T cells from suppression by platelet-derived thromboxane A2          (Yang et al., Nature 2025). These findings have contributed to understanding of clinical observations of aspirin’s anti-metastatic effects and received widespread media attention including BBC News. This work is particularly timely as it provides mechanistic insight for new randomised controlled trials including CaPP3 and Add-Aspirin, which are investigating the efficacy of low-dose aspirin in cancer prevention and recurrence.

Our research aims to uncover the molecular and cellular mechanisms underpinning immune regulation and cancer immunosuppression, with the goal of developing new approaches for cancer prevention and treatment of metastatic disease. Our work combines cutting-edge mouse models, advanced cellular and molecular techniques, and translational approaches to understand how the immune system can be harnessed for cancer prevention and treatment. Fundamental discoveries in immune suppression mechanisms will pave the way for new preventive and therapeutic strategies that could transform outcomes for patients at risk of developing cancer or those with existing metastatic disease.