The Center for Immuno-Oncology (CIO) investigates how our immune system reacts to cancer and what we can do to improve tumour immunity. We combine deep fundmental understanding of immunology with preclinical studies to translate new knowledge into clinical trials with the aim of developing new life-saving treatments for a spectrum of cancers.
Oxford’s long history of excellence in immunology is now focused on cancer, and CIO is the hub of the University-wide Oxford Cancer Immuno-Oncology Network (OCION) which links immuno-oncology researchers from multiple disciplines from across the University of Oxford, its affiliated hospitals and industrial partners.
CIO News
£1.7 million for vaccine to prevent lung cancer
2 April 2024
Oxford and UCL researchers seeking to create the world’s first vaccine to prevent lung cancer in people at high risk of the disease have been granted up to £1.7 million from Cancer Research UK and the CRIS Cancer Foundation.
Latest publications
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Sustainable active packaging developed using starch-based foam incorporating 1-Methylcyclopropene@α-Cyclodextrin.
Journal article
Jiang T. et al, (2025), Carbohydrate polymers, 347
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Dynamics of the blood plasma proteome during hyperacute HIV-1 infection
Journal article
Nazziwa J. et al, (2024), Nature Communications, 15
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Independent SAGE as an example of effective public dialogue on scientific research.
Journal article
Greenhalgh T. et al, (2024), Nature protocols
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Unlocking cancer vaccine potential: What are the key factors?
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Grant M. et al, (2024), Human vaccines & immunotherapeutics, 20
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Redefining PD1 as a guardian of stem-like T cells.
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Jackson M. and Parkes EE., (2024), Nat Rev Immunol
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Validity and timeliness of cancer diagnosis data collected during a prospective cohort study and reported by the English and Welsh cancer registries: a retrospective, comparative analysis.
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Jackson A. et al, (2024), The Lancet. Oncology, 25, 1476 - 1486
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The peptide selectivity model: Interpreting NK cell KIR-HLA-I binding interactions and their associations to human diseases
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Sim MJW. and Long EO., (2024), Trends in Immunology
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Targeting T-cell costimulation to the surface of tumor cells.
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Eguren-Santamaría I. et al, (2024), Clinical cancer research : an official journal of the American Association for Cancer Research
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Immunogenicity and Efficacy of Personalized Adjuvant mRNA Cancer Vaccines.
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Berraondo P. et al, (2024), Cancer discovery, 14, 2021 - 2024
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MHC Hammer reveals genetic and non-genetic HLA disruption in cancer evolution.
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Puttick C. et al, (2024), Nature genetics
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Novel H-2D<sup>b</sup>-restricted CD8 epitope derived from mouse MAGE-type antigen P1A mediates antitumor immunity in C57BL/6 mice.
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McAuliffe J. et al, (2024), Journal for immunotherapy of cancer, 12
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High proportion of PD-1 and CD39 positive CD8+ tissue resident T lymphocytes correlates with better clinical outcome in resected human oesophageal adenocarcinoma
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Hill SL. et al, (2024), Cancer Immunology, Immunotherapy, 73
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A retrospective analysis of the validity and timeliness of cancer diagnosis data collected during a prospective cohort study and reported by the English and Welsh cancer registries
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Jackson A. et al, (2024), The Lancet Oncology
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Implications of obesity and insulin resistance for the treatment of oestrogen receptor-positive breast cancer.
Journal article
Javed SR. et al, (2024), British journal of cancer
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Association Between Vitamin D Insufficiency and Impaired Bone Density Among Adolescents With Perinatally Acquired HIV Infection.
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Dzavakwa NV. et al, (2024), Open forum infectious diseases, 11
What's new for Oxford Cancer
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OCION: In conversation with Audrey Gerard
13 January 2025
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Oxford researchers develop blood test to enable early detection of multiple cancers
8 January 2025
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Alethiomics – using Artemis to hunt down blood cancers
6 January 2025
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Researchers provide a perspective on mapping the bone marrow using new spatial transcriptomic technologies
14 December 2024
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Predicting Response to Rectal Cancer Treatment through the S:CORT consortium
5 December 2024
Oxford Talks
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Monday, 27 January 2025, 10am to 12pm
Speakers: Professor Jeffrey Wasserstrom
Venue: Dickson Poon Building, Canterbury Road OX2 6LU
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Monday, 27 January 2025, 11am to 12.15pm
Speakers: Hannah Stovin, Shereece Linton-Ramsay
Venue: Magdalen College, High Street OX1 4AU
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Monday, 27 January 2025, 11.30am to 12.45pm
Speakers: Pedro Bordalo
Venue: Manor Road Building, Manor Road OX1 3UQ
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Monday, 27 January 2025, 12pm to 1pm
Speakers: Professor Ping-Chih Ho
Venue: Kennedy Institute of Rheumatology, Headington OX3 7FY
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Monday, 27 January 2025, 12pm to 1.15pm
Speakers: Dr Chun-Yi Lee
Venue: Dickson Poon Building, Canterbury Road OX2 6LU