Nicole Frumento
PhD
Postdoctoral Scientist
Research Interest:
My research focuses on the characterisation of B cell and antibodies responses in pre-clinical and clinical vaccine trials for HCV and SARS-CoV-2. I established serological assays to assess antibody binding and neutralisation to panels of relevant antigens.
Background:
My PhD in Cellular and Molecular Medicine at The Johns Hopkins University in 2018. During this time, I identified HCV antigens that are currently being tested in pre-clinical animal models at the University of Oxford.
Recent publications
The development of a pan-genotypic T cell vaccine against hepatitis C virus using heterologous prime-boost strategies.
Journal article
Strain R. et al, (2025), Hepatology (Baltimore, Md.)
Serum neutralization activity declines but memory B cells persist after cure of chronic hepatitis C.
Journal article
Nishio A. et al, (2022), Nature communications, 13
Mechanisms of HCV resistance to broadly neutralizing antibodies.
Journal article
Frumento N. et al, (2021), Current opinion in virology, 50, 23 - 29