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Publications

Publications from the Centre for Immuno-Oncology

Atom-level mechanism of tapasin-independent peptide editing by Major Histocompatibility Complex class I molecules

Turner S. et al, (2025)

Peptide-specific natural killer cell receptors.

Sim MJW. et al, (2025), Oxf Open Immunol, 6

The peptide selectivity model: Interpreting NK cell KIR-HLA-I binding interactions and their associations to human diseases

Sim MJW. and Long EO., (2024), Trends in Immunology

Identification and structural characterization of a mutant KRAS-G12V specific TCR restricted by HLA-A3.

Sim MJW. et al, (2024), European journal of immunology

Identification and Structural Characterization of a mutant KRAS-G12V specific TCR restricted by HLA-A3

Sim M. et al, (2024)

TCRs and AI: the future is now.

Sim MJW., (2023), Nat Rev Immunol

Innate receptors with high specificity for HLA class I-peptide complexes.

Sim MJW. et al, (2023), Science immunology, 8

T cells discriminate between groups C1 and C2 HLA-C.

Sim MJW. et al, (2022), eLife, 11

T Cell Recognition of Tumor Neoantigens and Insights Into T Cell Immunotherapy.

Sim MJW. and Sun PD., (2022), Frontiers in immunology, 13

T cells discriminate between groups C1 and C2 HLA-C

Sim M. et al, (2021)

High-affinity oligoclonal TCRs define effective adoptive T cell therapy targeting mutant KRAS-G12D.

Sim MJW. et al, (2020), Proceedings of the National Academy of Sciences of the United States of America, 117, 12826 - 12835

Human NK cell receptor KIR2DS4 detects a conserved bacterial epitope presented by HLA-C.

Sim MJW. et al, (2019), Proceedings of the National Academy of Sciences of the United States of America, 116, 12964 - 12973

HLA-C-restricted presentation of a conserved bacterial epitope to an innate NK cell receptor

Sim M. et al, (2019)

Lung Defense through IL-8 Carries a Cost of Chronic Lung Remodeling and Impaired Function.

Reynolds CJ. et al, (2018), American journal of respiratory cell and molecular biology, 59, 557 - 571

HLA-F: A New Kid Licensed for Peptide Presentation.

Sim MJW. and Sun PD., (2017), Immunity, 46, 972 - 974

Canonical and Cross-reactive Binding of NK Cell Inhibitory Receptors to HLA-C Allotypes Is Dictated by Peptides Bound to HLA-C.

Sim MJW. et al, (2017), Frontiers in immunology, 8

Canonical and cross-reactive binding of NK cell inhibitory receptors to HLA-C allotypes is dictated by peptides bound to HLA-C

Sim M. et al, (2016)

KIR2DL3 and KIR2DL1 show similar impact on licensing of human NK cells.

Sim MJW. et al, (2016), European journal of immunology, 46, 185 - 191

Autoantigen cross-reactive environmental antigen can trigger multiple sclerosis-like disease.

Reynolds CJ. et al, (2015), Journal of neuroinflammation, 12

A single amino acid change in inhibitory killer cell Ig-like receptor results in constitutive receptor self-association and phosphorylation.

Kumar S. et al, (2015), Journal of immunology (Baltimore, Md. : 1950), 194, 817 - 826

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