Publications from the Centre for Immuno-Oncology
Incoming HIV virion-derived Gag Spacer Peptide 2 (p1) is a target of effective CD8+ T cell antiviral responses.
Yang H. et al, (2021), Cell reports, 35
HLA-E-restricted, Gag-specific CD8+ T cells can suppress HIV-1 infection, offering vaccine opportunities.
Yang H. et al, (2021), Science immunology, 6
Therapeutic Vaccination Refocuses T-cell Responses Towards Conserved Regions of HIV-1 in Early Treated Individuals (BCN 01 study).
Mothe B. et al, (2019), EClinicalMedicine, 11, 65 - 80
Lessons from the Research in Viral Eradication of Reservoirs (RIVER) study: Impact of a therapeutic vaccine targeting conserved HIV epitopes on T cell function in treated primary infection
Kopycinski J. et al, (2019), JOURNAL OF THE INTERNATIONAL AIDS SOCIETY, 22, 20 - 21
Oral abstracts of the 22nd International AIDS Conference, 23-27 July 2018, Amsterdam, the Netherlands.
(2018), Journal of the International AIDS Society, 21 Suppl 6
Therapeutic Targeting of HIV Reservoirs: How to Give T Cells a New Direction.
Yang H. et al, (2018), Frontiers in immunology, 9
Evaluation of the immunogenicity and impact on the latent HIV-1 reservoir of a conserved region vaccine, MVA.HIVconsv, in antiretroviral therapy-treated subjects.
Hancock G. et al, (2017), Journal of the International AIDS Society, 20
Engineered affinity-enhanced immune-mobilising monoclonal T cell receptors (ImmTAVs) for HIV cure
Wallace Z. et al, (2017), HIV MEDICINE, 18, 7 - 7
Elimination of Latently HIV-infected Cells from Antiretroviral Therapy-suppressed Subjects by Engineered Immune-mobilizing T-cell Receptors.
Yang H. et al, (2016), Molecular therapy : the journal of the American Society of Gene Therapy, 24, 1913 - 1925
Defining the HLA class I-associated viral antigen repertoire from HIV-1-infected human cells.
Ternette N. et al, (2016), European journal of immunology, 46, 60 - 69
Aviremia 10 Years Postdiscontinuation of Antiretroviral Therapy Initiated During Primary Human Immunodeficiency Virus-1 Infection and Association With Gag-Specific T-Cell Responses.
Kinloch-de Loes S. et al, (2015), Open forum infectious diseases, 2
Identification of effective subdominant anti-HIV-1 CD8+ T cells within entire post-infection and post-vaccination immune responses.
Hancock G. et al, (2015), PLoS pathogens, 11
Engineered Gag-specific T-cell Receptors Redirect Polyclonal CD8(+) T-cells to Clear HIV-1-infected CD4(+) T-cells from ART-treated Patients.
Yang H. et al, (2014), AIDS research and human retroviruses, 30 Suppl 1
Evaluation of the Immunogenicity and Impact on the Latent HIV-1 Reservoir of an HIV Conserved Region Vaccine, MVA.HIVconsv, in HAART-treated Subjects
Moron-Lopez S. et al, (2014), AIDS RESEARCH AND HUMAN RETROVIRUSES, 30, A190 - A190
Emergence of a distinct HIV-specific IL-10-producing CD8+ T-cell subset with immunomodulatory functions during chronic HIV-1 infection.
Clutton G. et al, (2013), European journal of immunology, 43, 2875 - 2885
Linking genotype to phenotype on beads: high throughput selection of peptides with biological function.
Huang L-C. et al, (2013), Scientific reports, 3
Improved quantification of HIV-1-infected CD4+ T cells using an optimised method of intracellular HIV-1 gag p24 antigen detection.
Yang H. et al, (2013), Journal of immunological methods, 391, 174 - 178
Human leucocyte antigen-Bw4 and Gag-specific T cell responses are associated with slow disease progression in HIV-1B-infected anti-retroviral therapy-naive Chinese.
Li W-H. et al, (2013), Clinical and experimental immunology, 171, 298 - 306
Short communication: broader T cell responses directed against human immunodeficiency virus type 1 in infected Chinese individuals through blood-borne transmission in comparison with mucosal transmission.
Zhou D. et al, (2013), AIDS research and human retroviruses, 29, 89 - 93
The Antiviral Efficacy of CD8+T Cells in Early HIV-1 Infection Is Dependent on Targeting of Low Entropy Regions of the Viral Proteome
Hancock G. et al, (2013), AIDS RESEARCH AND HUMAN RETROVIRUSES, 29, A131 - A131