Publications from the Centre for Immuno-Oncology
HLA-E: Immune Receptor Functional Mechanisms Revealed by Structural Studies.
Gillespie GM. et al, (2025), Immunological reviews, 329
Identification and structural characterization of a mutant KRAS-G12V specific TCR restricted by HLA-A3.
Sim MJW. et al, (2024), European journal of immunology
Mucosal signatures of pathogenic T cells in HLA-B*27+ anterior uveitis and axial spondyloarthritis.
Paley MA. et al, (2024), JCI insight
High-throughput characterization of HLA-E-presented CD94/NKG2x ligands reveals peptides which modulate NK cell activation
Huisman BD. et al, (2023), Nature Communications, 14
Intracellular trafficking of HLA-E and its regulation.
He W. et al, (2023), The Journal of experimental medicine, 220
Publisher Correction: High-throughput characterization of HLA-E-presented CD94/NKG2x ligands reveals peptides which modulate NK cell activation.
Huisman BD. et al, (2023), Nature communications, 14
HLA class I signal peptide polymorphism determines the level of CD94/NKG2-HLA-E-mediated regulation of effector cell responses.
Lin Z. et al, (2023), Nature immunology, 24, 1087 - 1097
HLA-E-restricted SARS-CoV-2-specific T cells from convalescent COVID-19 patients suppress virus replication despite HLA class Ia down-regulation.
Yang H. et al, (2023), Science immunology, 8
Adaptive meets innate: CD8+ T cells kill MHC-I-negative tumour cells.
Peeters BWA. and Gillespie GM., (2023), Nature reviews. Immunology, 23
Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides.
Yang X. et al, (2022), Nature, 612, 771 - 777
Primary and secondary functions of HLA-E are determined by stability and conformation of the peptide-bound complexes.
Walters LC. et al, (2022), Cell reports, 39
Mouse and human antibodies bind HLA-E-leader peptide complexes and enhance NK cell cytotoxicity.
Li D. et al, (2022), Communications biology, 5
Discovery of HLA-E-Presented Epitopes: MHC-E/Peptide Binding and T-Cell Recognition.
Ruibal P. et al, (2022), Methods in molecular biology (Clifton, N.J.), 2574, 15 - 30
Incoming HIV virion-derived Gag Spacer Peptide 2 (p1) is a target of effective CD8+ T cell antiviral responses.
Yang H. et al, (2021), Cell reports, 35
HLA-E-restricted, Gag-specific CD8+ T cells can suppress HIV-1 infection, offering vaccine opportunities.
Yang H. et al, (2021), Science immunology, 6
Detailed and atypical HLA‐E peptide binding motifs revealed by a novel peptide exchange binding assay
Walters LC. et al, (2020), European Journal of Immunology, 50, 2075 - 2091
Interrogating the recognition landscape of a conserved HIV-specific TCR reveals distinct bacterial peptide cross-reactivity.
Mendoza JL. et al, (2020), eLife, 9