Publications from the Centre for Immuno-Oncology
Targeting MHC-E as a new strategy for vaccines and immunotherapeutics
Frueh K. et al, (2025), Nature Reviews Immunology
The antibodies 3D12 and 4D12 recognise distinct epitopes and conformations of HLA-E.
Brackenridge S. et al, (2024), Frontiers in immunology, 15
High-throughput characterization of HLA-E-presented CD94/NKG2x ligands reveals peptides which modulate NK cell activation
Huisman BD. et al, (2023), Nature Communications, 14
Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies.
Haynes BF. et al, (2023), Nature reviews. Immunology, 23, 142 - 158
Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides.
Yang X. et al, (2022), Nature, 612, 771 - 777
Immune signature atlas of vaccines: learning from the good responders.
Pedroza-Pacheco I. and McMichael AJ., (2022), Nature immunology, 23, 1654 - 1656
Primary and secondary functions of HLA-E are determined by stability and conformation of the peptide-bound complexes.
Walters LC. et al, (2022), Cell reports, 39
Mouse and human antibodies bind HLA-E-leader peptide complexes and enhance NK cell cytotoxicity.
Li D. et al, (2022), Communications biology, 5
HLA-E-restricted, Gag-specific CD8+ T cells can suppress HIV-1 infection, offering vaccine opportunities.
Yang H. et al, (2021), Science immunology, 6
CD4+ T Follicular Helper Cells in Human Tonsils and Blood Are Clonally Convergent but Divergent from Non-Tfh CD4+ Cells
Brenna E. et al, (2020), Cell Reports, 30, 137 - 152.e5
Capturing the antigen landscape: HLA-E, CD1 and MR1.
Ogg G. et al, (2019), Current opinion in immunology, 59, 121 - 129
Topological perspective on HIV escape.
McMichael AJ. and Carrington M., (2019), Science (New York, N.Y.), 364, 438 - 439
Author Correction: Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
Walters LC. et al, (2018), Nature communications, 9
Is a Human CD8 T-Cell Vaccine Possible, and if So, What Would It Take?
McMichael AJ., (2018), Cold Spring Harbor Perspectives in Biology, 10, a029124 - a029124
Corrigendum to ‘Unusual antigen presentation offers new insight into HIV vaccine design’ [Curr Opin Immunol 46 (2017) 75–81]
McMichael AJ. and Picker LJ., (2018), Current Opinion in Immunology, 53, 217 - 217
Legacy of the influenza pandemic 1918: The host T cell response
McMichael AJ., (2018), Biomedical Journal, 41, 242 - 248
Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
Walters LC. et al, (2018), Nature communications, 9
Lack of Truncated IFITM3 Transcripts in Cells Homozygous for the rs12252-C Variant That is Associated With Severe Influenza Infection
Makvandi-Nejad S. et al, (2018), The Journal of Infectious Diseases, 217, 257 - 262
The Role of MHC-E in T Cell Immunity Is Conserved among Humans, Rhesus Macaques, and Cynomolgus Macaques.
Wu HL. et al, (2018), Journal of immunology (Baltimore, Md. : 1950), 200, 49 - 60
A strongly selected mutation in the HIV-1 genome is independent of T cell responses and neutralizing antibodies
Liu D. et al, (2017), Retrovirology, 14