Immunotherapy of Cancer Visualized by Live Microscopy: Seeing Is Believing.
Teijeira A., Etxeberria I., Ponz-Sarvise M., Melero I.
The success of immunotherapy of cancer depends on several cellular events in the tumors that can be visualized by live microscopy strategies in experimental models. Taking advantage of advanced microscopy techniques, Lehmann and colleagues explore in this issue of CCR the mechanism of action of a novel bispecific mAb (TCB-CEA) that targets membrane-bound CEA and CD3ε. Clin Cancer Res; 22(17); 4277-9. ©2016 AACRSee related article by Lehmann et al., p. 4417.