Contact information
Research groups
Bevin Gangadharan
Senior Research Scientist
I have been working part-time in the Centre for Immuno-Oncology since September 2025, where I operate and maintain the liquid chromatography and mass spectrometry platforms used for immunopeptidomics research. Our centre is equipped with state-of-the-art instrumentation, including two Thermo Astral mass spectrometers, a Bruker timsTOF SCP, a Thermo Vanquish Neo UHPLC, two EvoSep Eno LCs and a Bruker nanoElute 2.
I completed my DPhil in Prof. Nicole Zitzmann’s lab in the Department of Biochemistry at the University of Oxford, where I specialised in proteomics, mass spectrometry and liver disease biomarker discovery. My first experience in proteomics was during industrial placements at SmithKline Beecham and GlaxoSmithKline, and I now have over two decades of experience in the field, spanning both discovery and targeted LC-MS/MS. I am also an inventor on three international patents relating to biomarkers for liver disease, including metabolic dysfunction-associated steatotic liver disease (MASLD), a condition that affects approximately one-third of the global population (over 1.3 billion people worldwide).
Alongside my role in the Centre for Immuno-Oncology, I continue to work part-time in the Department of Biochemistry, where I collaborate closely with the Medicine Quality Research Group led by Prof. Paul Newton on projects aimed at improving medicine quality and patient safety worldwide.
As part of the Vaccine Identity Evaluation (VIE) programme, I help develop novel low-cost technologies to identify falsified and substandard vaccines. I have led projects using MALDI-TOF mass spectrometry, hospital biochemical analysers, drying vaccines on black electricians’ tape, colorimetric assays and other innovative approaches to detect counterfeit and degraded vaccines.
I am also a member of the Oxford DEG/EG team, which addresses the global problem of diethylene glycol and ethylene glycol contamination in medicinal syrups. These contaminants have caused the deaths of hundreds of children worldwide. I have led the development of rapid (under two minutes) and low-cost (under £1 per test) tests for their detection.
In addition to my research, I have extensive experience mentoring undergraduate Part II, DPhil and postdoctoral researchers. I serve on the editorial board of Biomarker Research and am committed to communicating science both within academia and to the wider public. I regularly present my work at national and international conferences and participate in outreach activities that promote public engagement with science.
Recent publications
Ensuring vaccine cold chain integrity: A rapid and low-cost test for identifying heat-exposed sucrose-containing vaccines.
Journal article
Arman BY. et al, (2026), International journal of pharmaceutics: X, 11
Biochemical profiling provides a low-cost and globally accessible method to detect falsified vaccines and insulin.
Journal article
Brook J. et al, (2026), Scientific reports, 16
Rapid screening of ethylene glycol and diethylene glycol in raw materials and medicinal syrups using low-cost field deployable assays.
Journal article
Arman BY. et al, (2025), Scientific reports, 15
Handheld Spatially Offset Raman Spectroscopy for rapid non-invasive detection of ethylene glycol and diethylene glycol in medicinal syrups.
Journal article
Banerjee S. et al, (2025), Journal of pharmaceutical and biomedical analysis, 265
Proteomics Analysis of Peripheral Blood Mononuclear Cells from Patients in Early Dengue Infection Reveals Potential Markers of Subsequent Fluid Leakage.
Journal article
Perera N. et al, (2025), Viruses, 17
Ensuring vaccine cold chain integrity: A rapid and low-cost test for identifying heat-exposed sucrose-containing vaccines
Preprint
Arman BY. et al, (2025)
Identifying falsified COVID-19 vaccines by analysing vaccine vial label and excipient profiles using MALDI-ToF mass spectrometry.
Journal article
Arman BY. et al, (2025), NPJ vaccines, 10
Using matrix assisted laser desorption ionisation mass spectrometry combined with machine learning for vaccine authenticity screening.
Journal article
Clarke R. et al, (2024), NPJ vaccines, 9
Repurposing rapid diagnostic tests to detect falsified vaccines in supply chains.
Journal article
Bharucha T. et al, (2024), Vaccine, 42, 1506 - 1511
Innovative method for rapid detection of falsified COVID-19 vaccines through unopened vials using handheld Spatially Offset Raman Spectroscopy (SORS).
Journal article
Mosca S. et al, (2023), Vaccine, 41, 6960 - 6968
Deep Proteomics Network and Machine Learning Analysis of Human Cerebrospinal Fluid in Japanese Encephalitis Virus Infection.
Journal article
Bharucha T. et al, (2023), Journal of proteome research, 22, 1614 - 1629
Exploring the Potential of Iminosugars as Antivirals for Crimean-Congo Haemorrhagic Fever Virus, Using the Surrogate Hazara Virus: Liquid-Chromatography-Based Mapping of Viral N-Glycosylation and In Vitro Antiviral Assays.
Journal article
Tyrrell BE. et al, (2023), Pathogens (Basel, Switzerland), 12
Deep proteomics network and machine learning analysis of human cerebrospinal fluid in Japanese encephalitis virus infection
Preprint
Bharucha T. et al, (2022)
Assessing Antigen Structural Integrity through Glycosylation Analysis of the SARS-CoV-2 Viral Spike.
Journal article
Brun J. et al, (2021), ACS central science, 7, 586 - 593
Mass spectrometry-based proteomic techniques to identify cerebrospinal fluid biomarkers for diagnosing suspected central nervous system infections. A systematic review.
Journal article
Bharucha T. et al, (2019), The Journal of infection, 79, 407 - 418
Clinical diagnosis of non-alcoholic fatty liver disease using a panel of human blood protein biomarkers
Patent
Gangadharan B. et al, (2018)
Absolute quantitation of disease protein biomarkers in a single LC-MS acquisition using apolipoprotein F as an example.
Journal article
Kumar A. et al, (2017), Scientific reports, 7
Discovery and quantitation of novel liver fibrosis biomarkers in hepatitis C patients
Conference paper
Gangadharan B., (2017), 5th World Congress on Hepatitis & Liver Diseases & 2nd International Conference on Pancreatic Cancer & Liver Diseases, 6