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A first-in-human phase 1 clinical trial evaluating clinical activity and proof-of-mechanism of tobemstomig, a PD1-LAG3 bispecific antibody, in patients with CPI-experienced melanoma.

Journal article

Garralda E. et al, (2026), Clinical cancer research : an official journal of the American Association for Cancer Research

Upstream ORFs control TNFR1 abundance and tissue tolerance to TNF.

Journal article

Ma B. et al, (2026), Science immunology, 11

Intratumoral heterogeneity and immunotherapy resistance: clinical implications.

Journal article

Keenan BP. et al, (2026), Annals of oncology : official journal of the European Society for Medical Oncology, 37, 314 - 328

Safety, Feasibility, and Pharmacodynamic Activity of Intratumoral Injections of the Agonist Anti-CD137 (4-1BB) mAb Urelumab in Combination with Nivolumab.

Journal article

Sanmamed MF. et al, (2026), Clinical cancer research : an official journal of the American Association for Cancer Research, 32, 1036 - 1045

Risk Factors of Metabolic Dysfunction-associated Steatotic Liver Disease in a Cohort of Patients With Chronic Hepatitis B.

Journal article

Kalafateli M. et al, (2026), Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 24, 701 - 712.e8

Fine-tuning BACH2 dosage balances stemness and effector function to enhance antitumor T cell therapy.

Journal article

Conti AG. et al, (2026), Nature immunology, 27, 436 - 451

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