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Antigen Processing and Presentation- Elliott Group
My lab has worked on Major histocompatibility complex class I (MHC I) biology for over 35years. MHC I molecules protect us from infections and from cancer by binding to peptides and presenting them to receptors on the surface of cytotoxic T cells or Natural Killer cells. Recognition of peptide-MHC complexes by these receptors activate the cytotoxic cells, leading to the elimination of the cells on which the peptide-MHC complexes are expressed.