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Search results (13)

« Back to Publications

Fine-tuning BACH2 dosage balances stemness and effector function to enhance antitumor T cell therapy.

Conti AG. et al, (2026), Nature immunology, 27, 436 - 451

Aspirin prevents metastasis by limiting platelet TXA2 suppression of T cell immunity.

Yang J. et al, (2025), Nature, 640, 1052 - 1061

IFNγ Production by Functionally Reprogrammed Tregs Promotes Antitumor Efficacy of OX40/CD137 Bispecific Agonist Therapy.

Imianowski CJ. et al, (2024), Cancer research communications, 4, 2045 - 2057

Acquisition of suppressive function by conventional T cells limits antitumor immunity upon Treg depletion.

Whiteside SK. et al, (2023), Science immunology, 8

IL-2 is inactivated by the acidic pH environment of tumors enabling engineering of a pH-selective mutein.

Gaggero S. et al, (2022), Science immunology, 7

BACH2 restricts NK cell maturation and function, limiting immunity to cancer metastasis.

Imianowski CJ. et al, (2022), The Journal of experimental medicine, 219

CCR8 marks highly suppressive Treg cells within tumours but is dispensable for their accumulation and suppressive function.

Whiteside SK. et al, (2021), Immunology, 163, 512 - 520

A cell-based bioluminescence assay reveals dose-dependent and contextual repression of AP-1-driven gene expression by BACH2.

Vardaka P. et al, (2020), Scientific reports, 10

BACH2 drives quiescence and maintenance of resting Treg cells to promote homeostasis and cancer immunosuppression.

Grant FM. et al, (2020), The Journal of experimental medicine, 217

A distal enhancer at risk locus 11q13.5 promotes suppression of colitis by Treg cells.

Nasrallah R. et al, (2020), Nature, 583, 447 - 452

Granzyme B Is an Essential Mediator in CD8+ T Cell Killing of Theileria parva-Infected Cells.

Yang J. et al, (2019), Infection and immunity, 87, e00386 - e00318

Identification and annotation of bovine granzyme genes reveals a novel granzyme encoded within the trypsin-like locus.

Yang J. et al, (2018), Immunogenetics, 70, 585 - 597

IL-7-dependent maintenance of ILC3s is required for normal entry of lymphocytes into lymph nodes.

Yang J. et al, (2018), The Journal of experimental medicine, 215, 1069 - 1077