Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

We present detailed studies of human immunodeficiency virus (HIV)-specific cytotoxic T-lymphocyte (CTL) responses to clade A or C HIV type 1 in three donors infected in East Africa. We define several novel non-clade B CTL epitopes, including some restricted by HLA alleles common in Africans. Although cross-clade CTL recognition of these epitopes does occur, recognition can also be highly clade specific.

Original publication

DOI

10.1128/jvi.73.2.1708-1714.1999

Type

Journal article

Journal

Journal of virology

Publication Date

02/1999

Volume

73

Pages

1708 - 1714

Addresses

Molecular Immunology Group, Institute of Molecular Medicine, John Radcliffe Hospital, Oxford OX3 9DS, United Kingdom.

Keywords

T-Lymphocytes, Cytotoxic, Cells, Cultured, Humans, HIV-1, HIV Infections, Epitopes, T-Lymphocyte, Amino Acid Sequence, Molecular Sequence Data, Africa, Eastern, Female, Male