Paracetamol (acetaminofeno) intravenoso para cierre de conducto arterioso permeable en prematuros ≤ 32 semanas de gestación.
Gálvez-Cancino F.
ObjectiveTo identify the effectiveness of intravenous paracetamol for closure of patent ductus arteriosus in preterm ≤32 weeks gestation.MethodThis was a series of cases, a therapeutic intervention to closure was applied for ductus arteriosus >2 mm, identified by echocardiogram after 3 days of life, intravenous paracetamol was used, for a time range from 3 up to 6 days.ResultsThe prevalence of patent ductus arteriosus in ≤32 weeks gestation, was 40%. 21 patients were included, there was a predominance of female. Average age at diagnosis was 29 weeks gestation. The minimum weight 750 g, maximum 1350 g. Echocardiogram corroborated closure in 76%, intravenous paracetamol was more successful with 6 days treatment.ConclusionsThe prevalence of patent ductus arteriosus is directly proportional to the gestational age, being more common in women. Successful closure was 76%, this drug shows to be as effective as the first-choice drug, and a good alternative for intravenous therapy.