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ObjectiveTo identify the effectiveness of intravenous paracetamol for closure of patent ductus arteriosus in preterm ≤32 weeks gestation.MethodThis was a series of cases, a therapeutic intervention to closure was applied for ductus arteriosus >2 mm, identified by echocardiogram after 3 days of life, intravenous paracetamol was used, for a time range from 3 up to 6 days.ResultsThe prevalence of patent ductus arteriosus in ≤32 weeks gestation, was 40%. 21 patients were included, there was a predominance of female. Average age at diagnosis was 29 weeks gestation. The minimum weight 750 g, maximum 1350 g. Echocardiogram corroborated closure in 76%, intravenous paracetamol was more successful with 6 days treatment.ConclusionsThe prevalence of patent ductus arteriosus is directly proportional to the gestational age, being more common in women. Successful closure was 76%, this drug shows to be as effective as the first-choice drug, and a good alternative for intravenous therapy.

Original publication

DOI

10.24875/gmm.17002618

Type

Journal article

Journal

Gaceta medica de Mexico

Publication Date

01/2017

Volume

153

Pages

752 - 756

Addresses

Servicio de Cardiología Pediátrica, Hospital de Especialidades Pediátricas, Hospital Dr. Jesús Gilberto Gómez Maza, Tuxtla Gutiérrez, Chis., México.

Keywords

Humans, Ductus Arteriosus, Patent, Acetaminophen, Ultrasonography, Injections, Intravenous, Prevalence, Sex Distribution, Gestational Age, Infant, Newborn, Infant, Premature, Female, Male