Martinez-Riaño A., Mosteo L., Molero-Glez P., Marquez-Rodas I., Melero I.

The presence of moieties denoting viral infection is crucial to mount powerful cytotoxic T-cell immune responses acting through innate receptors such as Toll-like receptor 3 (TLR3). For cancer immunotherapy, several safe analogues of viral double-stranded RNA (dsRNA) are under clinical development following compelling evidence for efficacy in mouse models.

Double-stranded RNA to mimic viral infection for cancer immunotherapy.

Martinez-Riaño A., Mosteo L., Molero-Glez P., Marquez-Rodas I., Melero I.

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