Exploiting TCR Recognition of Shared Hotspot Oncogene-encoded Neoantigens.
Olivera I., Etxeberria I., Bolaños E., Gato-Cañas M., Melero I.
T-cell recognizable p53 hotspot mutations offer opportunities for immunotherapy and immune monitoring. Recognition of p53 mutations by peripheral blood CD8 and CD4 T lymphocytes has been revealed.See related article by Malekzadeh et al., p. 1267.