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In this issue of Immunity, Dong et al. (2009) describe the protein crystal structure heterodimer of tapasin and ERp57, which helps visualize the function of these proteins in loading of peptide antigens onto MHC class I molecules as part of the peptide loading complex within the endoplasmic reticulum.

More information Original publication

DOI

10.1016/j.immuni.2008.12.011

Type

Journal article

Publication Date

2009-01-01T00:00:00+00:00

Volume

30

Pages

1 - 2

Total pages

1

Addresses

C, a, n, c, e, r, , S, c, i, e, n, c, e, s, , D, i, v, i, s, i, o, n, ,, , S, c, h, o, o, l, , o, f, , M, e, d, i, c, i, n, e, ,, , U, n, i, v, e, r, s, i, t, y, , o, f, , S, o, u, t, h, a, m, p, t, o, n, ,, , S, o, u, t, h, a, m, p, t, o, n, ,, , U, K, .

Keywords

Endoplasmic Reticulum, Humans, Multiprotein Complexes, Peptides, Membrane Transport Proteins, Histocompatibility Antigens Class I, Models, Biological, Protein Disulfide-Isomerases